2023-11-09
炎症反应是机体对损伤作出的一种保护性反应,其目的是将损伤源破坏、稀释并清除,但与此同时也会引起不同程度的自身组织损伤。现有的抗炎药,如皮质类固醇和糖皮质激素等,一般都有副作用,并会在炎症组织中蓄积。
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2023-11-09
炎症反应是机体对损伤作出的一种保护性反应,其目的是将损伤源破坏、稀释并清除,但与此同时也会引起不同程度的自身组织损伤。现有的抗炎药,如皮质类固醇和糖皮质激素等,一般都有副作用,并会在炎症组织中蓄积。
2023-11-09
近期,中国科学院上海药物研究所于海军老师课题组在国际权威学术期刊Advanced materials上发表了题为“Engineering Stimuli-Activatable Boolean Logic Prodrug Nanoparticles for Combination Cancer Immunotherapy”的论文,本文首次报道了一种用于免疫调节剂(如免疫激活剂和免疫抑制剂)的肿瘤靶向协同输送及联合免疫治疗的布尔逻辑前药纳米粒(BLPNs)。
2023-11-09
文章题目:Bionanoparticle-Based Delivery in Antihypertensive Vaccine Mediates DC Activation through Lipid-Raft Reorganization 期 刊:Advanced Functional Materials(影响因子:15.621)
2023-11-09
银屑病俗称“牛皮癣”,是常见的皮肤慢性炎症性疾病。该病易于复发、无法根治、严重危害患者身心健康。临床上包括anti-TNF、anti-IL-17A/IL-17R、anti-IL-23等在内的抗体类药物靶向免疫系统及相关因子治疗银屑病有良好预期和效果,但副作用大,停药后疾病易反弹。
2023-11-09
2023-11-09
文章题目:Self-Amplified Drug Delivery with Light-Inducible Nanocargoes to Enhance Cancer Immunotherapy. 期 刊:Advanced Materials(影响因子:25.809)
2023-11-09
文章题目:Copper Tannic Acid Coordination Nanosheet: A Potent Nanozyme for Scavenging ROS from Cigarette Smoke. 期 刊:Small(影响因子:10.856)
2023-11-09
文章题目:Treatment with humanized selective CD19CAR-T cells shows efficacy in highly treated B-ALL patients who have relapsed after receiving murine-based CD19CAR-T therapies.期 刊:Clinical Cancer Research(影响因子:8.911)
2023-11-09
文章题目:Gold nanoparticles modulate the crosstalk between macrophages and periodontal ligament cells for periodontitis treatment. 期 刊:Biomaterials(影响因子:8.806)
2023-11-09
文章题目:Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade. 期 刊:Advanced materials(影响因子:21.950)
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