2025年2月,华中科技大学同济医学院附属同济医院汪道文教授团队与华大生命科学研究院方晓东研究员团队在Signal Transduction and Targeted Therapy(IF=40.8)上发表题为“Spatiotemporal transcriptomics elucidates the pathogenesis of fulminant viral myocarditis.(时空转录组学揭示暴发性病毒性心肌炎的发病机制)”的研究。
该研究利用华大时空组学(Stereo-seq)技术和单核RNA测序(snRNA-seq)技术,在CVB3病毒感染的小鼠模型中绘制出FM时空动态基因图谱。研究发现,间皮细胞是CVB3的初始靶细胞,并解析了免疫级联反应如何引爆炎症反应和心肌细胞死亡“风暴"。
该项研究中,使用了欣博盛生物(NeoBioscience Technology Co, Ltd)的Mouse IFN-γ ELISA Kit,用于检测FM小鼠心脏组织中相关指标的含量。
货号 | 产品名称 | 灵敏度 | 检测范围 |
QuantiCyto® Mouse IFN-γ ELISA kit (小鼠γ干扰素) | 3.9pg/ml | 7.8-500pg/ml |
欣博盛生物作为供应商,为该研究提供了高质量ELISA试剂盒。这不仅帮助了研究团队在实验中取得可靠的数据,也彰显了我们致力于支持生物医学领域科研进展的承诺。
2025年2月文献引用
1. Spatiotemporal transcriptomics elucidates the pathogenesis of fulminant viral myocarditis.(Signal Transduction and Targeted Therapy, IF=40.8)
发表时间:2025/2/10
作者单位:华中科技大学同济医学院附属同济医院
引用产品:Mouse IFN-γ ELISA kit
样本类型:心脏组织
https://www.nature.com/articles/s41392-025-02143-9
2. Synergistic role of gut-microbial L-ornithine in enhancing ustekinumab efficacy for Crohn’s disease.(Cell Metabolism, IF=27.7)
发表时间:2025/2/19
作者单位:上海交通大学医学院附属仁济医院
引用产品:Mouse IL-17F ELISA Kit
样本类型:mTh17细胞
https://www.cell.com/cell-metabolism/abstract/S1550-4131(25)00007-5
3. Cryo-Shocked Tumor-Reprogrammed Sonosensitive Antigen-Presenting Cells Improving Sonoimmunotherapy via T Cells and NK Cells Immunity.(ADVANCED MATERIALS, IF=27.4)
发表时间:2025/2/16
作者单位:同济大学医学院
引用产品:Mouse IFN-γ and TNF-α ELISA kits
样本类型:4T1细胞异种移植模型
https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/adma.202413289
4. Parabacteroides distasonis promotes liver regeneration by increasing β-hydroxybutyric acid (BHB) production and BHB-driven STAT3 signals.(Acta Pharmaceutica Sinica B, IF=14.7)
发表时间:2025/2/10
作者单位:南方医科大学
引用产品:Mouse IL-6 ELISA kit
样本类型:肝脏组织
https://www.sciencedirect.com/science/article/pii/S2211383525000309
5. Biomimetic Nanoplatform for Targeted Rheumatoid Arthritis Therapy: Modulating Macrophage Niches Through Self-Sustaining Positive Feedback-Driven Drug Release Mechanisms.(Advanced Science, IF=14.3)
发表时间:2025/2/22
作者单位:深圳工业大学
引用产品:Mouse TNF-α, IL-1β and IL-6 ELISA kits
样本类型:血清样本
https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/advs.202416265
6. Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation-Associated Microglial Response.(Advanced Science, IF=14.3)
发表时间:2025/2/8
作者单位:中国中医科学院针灸研究所
引用产品:Mouse TNF-α and IL-6 ELISA kits
样本类型:BV2细胞
https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/advs.202405263
7. Tailoring Tumor Cell Golgi Apparatus-Targeting Self-Assembled Peptide for Effective Immunotherapy via Reshaping MIF-Mediated Immunosuppressive Network.(Advanced Science, IF=14.3)
发表时间:2025/2/5
作者单位:南方医科大学
引用产品:Mouse TNF-α ELISA kit
样本类型:4T1细胞异种移植模型
https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/advs.202415133
8. Brain-targeted delivery of Acetyl-11-Keto-β-Boswellic acid with enhanced anti-inflammatory efficacy via blood-brain barrier peptide shuttle PepH3.(CHEMICAL ENGINEERING JOURNAL, IF=13.3)
发表时间:2025/2/18
作者单位:空军军医大学西京医院
引用产品:Rat IL-1β, IL-6 and TNF-α ELISA kits
样本类型:血浆样本
https://www.sciencedirect.com/science/article/pii/S1385894725014858
9. Counteracting immunodepression by extracellular matrix hydrogel to promote brain tissue remodeling and neurological function recovery after traumatic brain injury.(BIOMATERIALS, IF=12.8)
发表时间:2025/2/8
作者单位:华东理工大学
引用产品:Mouse BDNF, NGF, SDF-1α , TNF-α, IL-1β, IL-6, IL-4 and IL-10 ELISA kits
样本类型:脑组织
https://www.sciencedirect.com/science/article/pii/S0142961225001000
10. Lipid metabolism of apoptotic vesicles accelerates cutaneous wound healing by modulating macrophage function.(JOURNAL OF NANOBIOTECHNOLOGY, IF=10.6)
发表时间:2025/2/12
作者单位:第四军医大学
引用产品:Mouse TNF-ɑ, VEGF and TGF-β ELISA kits
样本类型:巨噬细胞培养上清液
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-025-03194-4
11. Polyphenol-based pH-responsive nanoparticles enhance chemo-immunotherapy in pancreatic cancer.(JOURNAL OF CONTROLLED RELEASE, IF=10.5)
发表时间:2025/2/16
作者单位:兰州大学第二医院
引用产品:Mouse IFN-γ ELISA kit
样本类型:胰腺癌自发性肿瘤异种移植模型
https://www.sciencedirect.com/science/article/pii/S0168365925001348
12. A stimuli–responsive immunostimulant to activate chemo-immunotherapeutic effects by inducing DNA damage and STING activation.(JOURNAL OF COLLOID AND INTERFACE SCIENCE, IF=9.4)
发表时间:2025/2/26
作者单位:南方医科大学珠江医院
引用产品:Mouse IL-6 ELISA kit
样本类型:4T1细胞
https://www.sciencedirect.com/science/article/pii/S0021979725005430
13. Tumor vascular endothelial cells promote immune escape by upregulating PD-L1 expression via crosstalk between NF-κB and STAT3 signaling pathways in nasopharyngeal carcinoma.(Cell Death & Disease, IF=8.1)
发表时间:2025/2/25
作者单位:中山大学
引用产品:Human IFN-γ, TNF-α, Granzyme B and Perforin ELISA kits
样本类型:人脐静脉内皮细胞
https://www.nature.com/articles/s41419-025-07444-z
14. Usp11 maintained the survival of marginal zone B cells under ionizing radiation by deubiquitinating DLL1 and JAG2.(Cell Death & Disease, IF=8.1)
发表时间:2025/2/4
作者单位:苏州大学
引用产品:Mouse IgG ELISA kit
样本类型:血清样本
https://www.nature.com/articles/s41419-025-07377-7
15. LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress.(Cell Death & Disease, IF=8.1)
发表时间:2025/2/3
作者单位:中山大学附属第一医院
引用产品:Mouse TNF-α, IL-6 and IL-1β ELISA kits
样本类型:内皮细胞、巨噬细胞培养上清液
https://www.nature.com/articles/s41419-025-07394-6
16. A thermally stable bioactive chitosan scaffold with pH-responsive exosome adsorption and release function promotes wound healing.(INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, IF=7.7)
发表时间:2025/2/28
作者单位:中国人民解放军总医院
引用产品:Mouse IL-1β, TNF-α and IL-10 ELISA kits
样本类型:RAW264.7细胞
https://www.sciencedirect.com/science/article/pii/S0141813025021038
17. Comparation of brain-targeting chitosan/sodium tripolyphosphate and ovalbumin/sodium carboxymethylcellulose nanoparticles on dihydromyricetin delivery and cognitive impairment in obesity-related Alzheimer's disease.(INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, IF=7.7)
发表时间:2025/2/26
作者单位:福州大学
引用产品:Mouse IL-1β and TNF-α ELISA kits
样本类型:脑组织;肝脏组织
https://www.sciencedirect.com/science/article/pii/S0141813025020689
18. Potentilla anserina L. polysaccharide ameliorates LPS-induced acute lung injury and relevant intestinal mucosal barrier impairment.(INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, IF=7.7)
发表时间:2025/2/6
作者单位:山东大学齐鲁医院
引用产品:Mouse IL-1β, IL-6 and TNF-α ELISA kits
样本类型:血清样本;肺组织
https://www.sciencedirect.com/science/article/pii/S0141813025012164
19. Human dental follicle stem cell-derived exosomes reduce root resorption by inhibiting periodontal ligament cell pyroptosis.(Stem Cell Research & Therapy, IF=7.1)
发表时间:2025/2/21
作者单位:四川大学华西口腔医院
引用产品:Human IL-1β ELISA kit
样本类型:人牙周膜干细胞
https://link.springer.com/article/10.1186/s13287-025-04216-6
20. Construction of tetravalent bispecific Tandab (CD3/BCMA)-secreting human umbilical cord mesenchymal stem cells and its efficiency in the treatment of multiple myeloma.(Stem Cell Research & Therapy, IF=7.1)
发表时间:2025/2/12
作者单位:南昌大学第一附属医院
引用产品:Human IL-2, IFN-γ and TNF-α ELISA kits
样本类型:间充质干细胞
https://stemcellres.biomedcentral.com/articles/10.1186/s13287-025-04212-w
21. T3SS translocon induces pyroptosis by direct interaction with NLRC4/NAIP inflammasome.(eLife, IF=6.4)
发表时间:2025/2/14
作者单位:中国科学院海洋研究所
引用产品:Human IL-1β ELISA kit
样本类型:巨噬细胞培养上清液
https://elifesciences.org/articles/100820
22. HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.(MOLECULAR MEDICINE, IF=6)
发表时间:2025/2/9
作者单位:西安市红会医院
引用产品:Rat IL-1β, IL-18, IL-6, IL-10 and TNF-α ELISA kits
样本类型:脊髓组织,小胶质细胞
https://molmed.biomedcentral.com/articles/10.1186/s10020-025-01086-9
23. Microsphere-integrated hydrogel microneedle patch for sustained methotrexate delivery in the long-term management of atopic dermatitis.(EUROPEAN POLYMER JOURNAL, IF=5.8)
发表时间:2025/2/28
作者单位:天津大学
引用产品:Mouse IgE and IL-4 ELISA kits
样本类型:血清样本
https://www.sciencedirect.com/science/article/pii/S001430572500165X
24. Identification and Validation of Key Amino Acids in IgE Linear Epitopes of β-Lactoglobulin: Comparison of Recognition Patterns of Chinese Bovine Milk-Allergic Sera with Different Symptoms.(JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, IF=5.7)
发表时间:2025/2/23
作者单位:南昌大学
引用产品:Human IL-4 and IL-6 ELISA kits
样本类型:KU812细胞
https://pubs.acs.org/doi/abs/10.1021/acs.jafc.4c11999
25. Screening Human IgE Epitopes on α-Lactalbumin and Developing Specific Detection Tools for Enhanced Allergen Detection in Food Matrices.(JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, IF=5.7)
发表时间:2025/2/10
作者单位:南昌大学
引用产品:TMB (standard sensitivity), HRP- Streptavidin Concentrate
https://pubs.acs.org/doi/abs/10.1021/acs.jafc.4c11921
26. Structural Characterization of APSN from Astragalus membranaceus and Its Potential Therapeutic Effect on Immune Dysregulation and Tissue Damage.(JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, IF=5.7)
发表时间:2025/2/7
作者单位:南方科技大学
引用产品:Mouse TNF-α and IL-1β ELISA Kits
样本类型:RAW264.7细胞
https://pubs.acs.org/doi/abs/10.1021/acs.jafc.4c08632
27. Preparation of the Hypoallergenic Enzymatic Hydrolyzate of Cra a 4 with the Potential to Induce Immune Tolerance.(JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, IF=5.7)
发表时间:2025/2/5
作者单位:集美大学
引用产品:Mouse IL-4, IFN-γ, IL-10 and TGF-β1 ELISA kits
样本类型:T细胞
https://pubs.acs.org/doi/abs/10.1021/acs.jafc.4c12433
28. TFF3 facilitates dormancy of anti-estrogen treated ER+ mammary carcinoma.(Communications Medicine, IF=5.4)
发表时间:2025/2/21
作者单位:清华大学清华-伯克利深圳研究院
引用产品:Annexin V-FITC/PI apoptosis assay kit
https://www.nature.com/articles/s43856-024-00710-9
29. Circular RNA ZNF277 Sponges miR-378d to Inhibit the Intracellular Survival of Mycobacterium tuberculosis by Upregulating Rab10.(Cells, IF=5.1)
发表时间:2025/2/12
作者单位:华中农业大学
引用产品:Human IL-1β, IL-6 and TNF-α ELISA kits
样本类型:THP-1细胞
https://www.mdpi.com/2073-4409/14/4/262
30. Integration of network pharmacology, bioinformatics and experimental verification strategy to discover the pharmacological mechanisms of mogroside acts against pharyngitis.(JOURNAL OF ETHNOPHARMACOLOGY, IF=4.8)
发表时间:2025/2/14
作者单位:澳门科技大学
引用产品:Mouse TNF-α, IL-1β, IL-4, IL-6 and IL-10 ELISA kits
样本类型:RAW264.7细胞
https://www.sciencedirect.com/science/article/pii/S0378874125001837
31. A newly discovered bioactive equivalence of combinatorial components of Angong Niuhuang pills improves ischemic stroke via the PI3K/AKT axis.(JOURNAL OF ETHNOPHARMACOLOGY, IF=4.8)
发表时间:2025/2/6
作者单位:中国药科大学
引用产品:Mouse IL-6, IL-1β and TNF-α ELISA kits
样本类型:血清样本
https://www.sciencedirect.com/science/article/pii/S0378874125001369
32. Effect of Food Matrix on Regulation of Intestinal Barrier and Microbiota Homeostasis by Polysaccharides Sulfated Carrageenan.(Foods, IF=4.7)
发表时间:2025/2/14
作者单位:泉州师范学院
引用产品:Mouse IL-10, TNF-α and CRP ELISA kits
样本类型:血清样本
https://www.mdpi.com/2304-8158/14/4/635
33. Anti-citrullinated procollagen C-endopeptidase enhancer antibody: a potential biomarker for seronegative rheumatoid arthritis.(RHEUMATOLOGY, IF=4.7)
发表时间:2025/2/5
作者单位:北京大学人民医院
引用产品:TMB (standard sensitivity)
34. Metagenomic Sequencing Combined with Metabolomics to Explore Gut Microbiota and Metabolic Changes in Mice with Acute Myocardial Infarction and the Potential Mechanism of Allicin.(Drug Design Development and Therapy, IF=4.7)
发表时间:2025/2/2
作者单位:中日友好医院
引用产品:Mouse IL-18 and IL-1β ELISA kits
样本类型:血清样本
https://www.tandfonline.com/doi/abs/10.2147/DDDT.S504884
35. Study on the Optimization of an Extraction Process of Two Triterpenoid Saponins in the Root of Rosa laevigata Michx. and Their Protective Effect on Acute Lung Injury.(Pharmaceuticals, IF=4.3)
发表时间:2025/2/13
作者单位:广西中医药大学
引用产品:Mouse TNF-α and IL-6 ELISA kits
样本类型:肺组织
https://www.mdpi.com/1424-8247/18/2/253
36. Angesinenolide B, A Phthalide Dimeric Peroxide, Exerts Anti-Inflammatory Properties by Suppressing MAPK/STATs Signaling Pathways and ROS Production.(Journal of Inflammation Research, IF=4.2)
发表时间:2025/2/2
作者单位:新乡医学院
引用产品:Mouse TNF-α ELISA Kit
样本类型:RAW 264.7细胞
https://www.tandfonline.com/doi/abs/10.2147/JIR.S501313
37. Optimizing phage therapy for carbapenem-resistant Enterobacter cloacae bacteremia: insights into dose and timing.(ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, IF=4.1)
发表时间:2025/2/26
作者单位:南京中医药大学第二附属医院
引用产品:Mouse IL-1β, TNF-α and IL-6 ELISA kits
样本类型:血清样本
https://journals.asm.org/doi/abs/10.1128/aac.01683-24
38. Tumor-Targeted Delivery of PD-1-Displaying Bacteriophages by Escherichia coli for Adjuvant Treatment of Colorectal Cancer.(ACS Synthetic Biology, IF=3.7)
发表时间:2025/2/10
作者单位:华东理工大学
引用产品:Human IFN-γ ELISA kit
样本类型:CD4+ T细胞
https://pubs.acs.org/doi/abs/10.1021/acssynbio.4c00570
39. Moscatilin alleviates oxidative stress and inflammatory response of Müller cells in diabetic retinopathy through suppressing the p38 mitogen-activated protein kinase/c-Jun N-terminal kinase and nuclear factor kappa-B signaling pathways.(Journal of Cell Communication and Signaling, IF=3.6)
发表时间:2025/2/19
作者单位:徐州市第一人民医院
引用产品:Mouse VEGF, TNF-α, IL-6 and IL-1β ELISA kits
样本类型:视网膜组织
https://onlinelibrary.wiley.com/doi/abs/10.1002/ccs3.12059
40. CAR-NK cells with dual targeting of PD-L1 and MICA/B in lung cancer tumor models.(BMC CANCER, IF=3.4)
发表时间:2025/2/25
作者单位:新乡医学院
引用产品:Human TNF-α, IFN-γ, perforin and Granzyme B ELISA kits
样本类型:H1299细胞
https://pmc.ncbi.nlm.nih.gov/articles/PMC11853679/
41. Downregulated TRIM35 Alleviates Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress and Inflammation via Inhibiting TLR4/NF-κB Pathway.(CARDIOVASCULAR DRUGS AND THERAPY, IF=3.1)
发表时间:2025/2/15
作者单位:宁波大学第一附属医院
引用产品:Mouse IL-1β, IL-6 and TNF-α ELISA kits
样本类型:血清样本
https://link.springer.com/article/10.1007/s10557-025-07672-7
42. Cerebrospinal fluid interleukin-6 may be a biomarker for conversion of clinically isolated syndrome to neuromyelitis optica spectrum disorder.(Multiple Sclerosis and Related Disorders, IF=2.9)
发表时间:2025/2/2
作者单位:首都医科大学附属北京天坛医院
引用产品:Human TGF-β1 ELISA kit
样本类型:脑脊液
https://www.sciencedirect.com/science/article/pii/S2211034825000574
43. Normal butanol fraction of Polygonum hydropiper L. flavonoids reduces inflammation caused by PCV2 infections in cell and mouse models.(Frontiers in Veterinary Science, IF=2.6)
发表时间:2025/2/4
作者单位:广西大学
引用产品:Mouse MCP-1, IL-6, IL-8, IL-10 and TNF-α ELISA kits
样本类型:血清样本
https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2025.1539448/full
44. Structural Characteristics of Ziziphus jujuba dates Polysaccharide and Its Protective Effect Against Colitis.(CHEMISTRY & BIODIVERSITY, IF=2.3)
发表时间:2025/2/1
作者单位:安阳工学院
引用产品:Mouse TNF-α, IL-6, IL-10 and IL-12 ELISA kits
样本类型:血清样本
https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.202402568
45. Gastrodin plays a protective role in alleviating hepatic ischemia reperfusion injury by regulating heme oxygenase-1 expression.(BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, IF=1.9)
发表时间:2025/2/3
作者单位:昆明医科大学第一附属医院
引用产品:Mouse IL-6 ELISA kit
样本类型:肝脏组织